A few weeks ago, we gathered at Emily’s house for a brunch to recognize current postdocs Vladimir and Spencer’s time with the lab, and to wish them well in their newly acquired faculty appointments! To…
Gang, S.S., Grover, M., Reddy, K.C., Raman, D., Chang, Y.T., Ekiert, D.C., Barkoulas, M., Troemel, E.R. A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans. PLoS Genetics 18.10 (2022).
Congratulations to Postdoc Spencer Gang on his latest publication characterizing a pals-25 gain-of-function allele with a premature stop.
In collaboration with the Barkoulas lab, we found that this allele activates two related gene expression programs: the Oomycete Recognition Response in the epidermis, and the Intracellular Pathogen Response in the intestine.
Click the publication title to find out more!